Well it seems to run fine on everything, sad the visuals are so weak:
e.g.
http://www.hardocp.com/image.html?image=MTMxNDAzNjMxNlNtcEpVSVVXR1lfM18xMV9sLmpwZw==
Where's the shadows gone - can't see any character shadows let alone shadowing on the clothes to give them some depth. Skin and hair look exactly the same as cloth - they don't look like skin or hair. The clothes look completely flat, no obvious layering. The ground and walls are just flat textures not tessellated or even bump mapped. Everything is very square. No bloom or hdr effect of the light shining though the door at all. The colours are UE3 brown (I know it's not UE3 but it reminds me of GOW and other games where they only had a pallet of browns).
Still if game play is good visuals don't matter too much.
You bring up some of the main drawbacks, visually speaking, that i've noticed in my ~8hrs of gameplay so far. I've noticed the lack of shadows as a drawback to immersion. Some of the textures, clothing especially are extremely bland and without character. Though some characters are done extremely well here, Megan Reed and her mom come to mind as two characters that really felt alive to me.
Off topic here a bit, but what I would like to see in this and other games are perhaps some debri being blown across a city street. Waving flags in front of a police station are nice, but i'd like to have some more visual cues that the world is dynamic and breathing. Dues Ex: HR has areas that feel depressing due to a void created from the lack of a vibrant breathing world.
Beyond those drawbacks, i'm still fascinated by the world and my musings above amount to mere nitpicking's when I consider how enthralled and immersed I have gotten so far with my playtime in this gem.
Also, changing my FOV to 90 from 75 for a 16:9 monitor helped the feel quite a bit. I'm trying 90 and 95. 75 felt like I was playing with blinders on.