There is a difference between responding to something you see, and trying to track something with your mouse. It does feel sluggish when you move your mouse with v-sync on, especially with a 60hz computer. This can cause you to have a harder time tracking a target. You will find the mouse is always slightly behind where you want it to go, and when you stop it over shoots slightly. Granted, it may not be huge, but it is there.
To add to this, some people can get sick as a result of this latency. I get sick from this latency when my FPS are lower than 80 FPS, I'll get sick after a certain amount of time. At 30 FPS, I get sick in 5 mins. At 60 FPS, I last 30-60 mins and at 80+ fps, it goes away. This is due to latency and the sluggish feeling it has at lower FPS.
Due to my problem, I have a high end computer, and a 120hz monitor. Together, it greatly improves my experience.
If this claimed major problem with input latency makes you sick then screen tearing must seriously mess you up.
Seriously how far can your mouse go in 1/60th of a second?
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