NON_POLITICAL China Coronavirus THREAD

Page 303 - Seeking answers? Join the AnandTech community: where nearly half-a-million members share solutions and discuss the latest tech.

Ichinisan

Lifer
Oct 9, 2002
28,298
1,235
136
At the end of January I proposed everyone get it. By the end of February it is over with presuming repeat infections (from mutation) do not occur.
Infecting everyone over a short period would have just as many mutations as the same number of people over a longer period. So letting everyone get infected will not reduce the likelihood of mutation.
 
  • Like
Reactions: Meghan54

K1052

Elite Member
Aug 21, 2003
53,813
48,532
136
Well my antibody test turned out negative and the possibility of a false negative with this test is negligible so I guess we may have just encountered influenza B. The 2019-20 vaccine was only partially effective for B so even though I got the shot could have still ended up with it.

Quest did process it remarkably quickly. 16 hours from sample collection to results in their app which included a 3 hour trip for it from Austin to their Dallas lab.
 

kn51

Senior member
Aug 16, 2012
708
123
106
One thing I noticed that is weird (well not really weird given the circumstances) is how little mail we are getting. As in sort of junk, flyers, etc. I have informed delivery and this is the first time it will show one piece being delivered.
 

Mai72

Lifer
Sep 12, 2012
11,562
1,742
126
I was at the supermarket and a guy standing next to me was breathing very hard. I was like WTF, and got away quickly.

I don't want the Ronna. :(
 

rh71

No Lifer
Aug 28, 2001
52,844
1,049
126
https://local.theonion.com/man-just-buying-one-of-every-cleaning-product-in-case-t-1842493766

I'm not posting this to be political....just posting because if you've watched the news in the last 24 hours, you may have heard something like this....now look at the date on the "article". 🤣

Wyoming... is that red or blue? HMMMMMM.

just so me and my family will be ready if the president announces one of these things can treat Chinese virus,”
The man bought Drano. For his family. To ingest...?

WHAT IS EVEN THIS WORLD?!?!?!
 

Ichinisan

Lifer
Oct 9, 2002
28,298
1,235
136
Unfortunate but not entirely surprising. Anti virals are more helpful earlier on instead of likely advanced cases. Still have to wait to see what the moderate trial turns up.


I don't know how people misinterpreted the earlier statements as "promising." They said "only two died" (in a test with only 125 participants).

2 deaths in 125

1.6% death rate

Seems bad.

I would assume the previously calculated death rates had a similar mix of severe + mild cases -- weighing heavily toward the severe cases because people who show severe symptoms are the most likely to be tested + confirmed.
 

K1052

Elite Member
Aug 21, 2003
53,813
48,532
136
I don't know how people misinterpreted the earlier statements as "promising." They said "only two died" (in a test with only 125 participants).

Without knowing the severity of the symptoms and what interventions the patients had already received compared to the mortality for a comparable group it seems difficult to for us outside the trial to determine if that's good or bad even though the doctor's comments seemed to exhibit optimism.
 

CZroe

Lifer
Jun 24, 2001
24,195
857
126

I'm still operating under the assumption that you won't catch it again unless it drifts/mutates like endemic flu.

Infecting everyone over a short period would have just as many mutations as the same number of people over a longer period. So letting everyone get infected will not reduce the likelihood of mutation.

...unless everyone was infected all at once from a controlled source so that most mutations would never get beyond the host they developed in.
 

CZroe

Lifer
Jun 24, 2001
24,195
857
126
I know this isn't supposed to be political, but the right kept swearing this is what was going to happen under Obama.
View attachment 20136

(Don't take this seriously)

Because Islam is the dominant religion in the world, I think we can see why the virus disproportionately affect men. ;)

J/K

Wyoming... is that red or blue? HMMMMMM.


The man bought Drano. For his family. To ingest...?

WHAT IS EVEN THIS WORLD?!?!?!

It's satire.
 
  • Like
Reactions: Scarpozzi

purbeast0

No Lifer
Sep 13, 2001
53,757
6,635
126
Wyoming... is that red or blue? HMMMMMM.


The man bought Drano. For his family. To ingest...?

WHAT IS EVEN THIS WORLD?!?!?!
You've been here since the glory days and don't know that The Onion is a satirical news site?
 

killster1

Banned
Mar 15, 2007
6,205
475
126

I'm still operating under the assumption that you won't catch it again unless it drifts/mutates like endemic flu.



...unless everyone was infected all at once from a controlled source so that most mutations would never get beyond the host they developed in.
there are two strains of the virus and many accounts of people being reinfected.. not a widespread reinfection tho so its hard to tell, but im with them on saying you can be infected twice.
 

K1052

Elite Member
Aug 21, 2003
53,813
48,532
136
there are two strains of the virus and many accounts of people being reinfected.. not a widespread reinfection tho so its hard to tell, but im with them on saying you can be infected twice.

Going by South Korea it looks like some reactivation is happening not reinfection. The people who are reactivating do not, so far, appear to be contagious. They are just showing positive results again on PCR tests.
 
  • Like
Reactions: killster1
Dec 10, 2005
29,665
15,243
136
I'm still operating under the assumption that you won't catch it again unless it drifts/mutates like endemic flu.
Why would you operate under this assumption? Influenza is a different type of virus, so it doesn't seem like a relevant model to follow.

There doesn't seem to be evidence to support long-term immunity, since the follow-up time is too short for individuals who have recovered. On the other hand, we know from immunity to other coronavirii that immune memory tends to be somewhat short. We don't have data to show that COVID-19 will have the same effect on the immune system, but based on the more closely-related virii, it's a good possibility that COVID-19 will have the same immune effect.
 

CZroe

Lifer
Jun 24, 2001
24,195
857
126
there are two strains of the virus and many accounts of people being reinfected.. not a widespread reinfection tho so its hard to tell, but im with them on saying you can be infected twice.
Me too... if that was what they said.

I've been aware of the different strains for several weeks now and am concerned with the chance for reassortment/recombination with other coronaviruses (antigenic shift) or even just run-of-the-mill random mutations (antigenic drift). It's certainly possible that multiple strains explain the reinfections, which is exactly why I am hesitant to believe that there is no immunity or antibody protection after infection. If you can't be infected by the same strain twice and it requires a new strain to get through your defenses then natural immunity is still possible and a vaccine can still stoke an immune response for multiple strains at once (much like the flu vaccine).

What they said was that there was no evidence that antibodies give you any immunity, not that reinfections were caused by a different strain. If you immune system could not develop immunity then it would have a very difficult time fighting the virus off in the first place.


Why would you operate under this assumption? Influenza is a different type of virus, so it doesn't seem like a relevant model to follow.

There doesn't seem to be evidence to support long-term immunity, since the follow-up time is too short for individuals who have recovered. On the other hand, we know from immunity to other coronavirii that immune memory tends to be somewhat short. We don't have data to show that COVID-19 will have the same effect on the immune system, but based on the more closely-related virii, it's a good possibility that COVID-19 will have the same immune effect.

See above.
 
Dec 10, 2005
29,665
15,243
136
What they said was that there was no evidence that antibodies give you any immunity, not that reinfections were caused by a different strain. If you immune system could not develop immunity then it would have a very difficult time fighting the virus off in the first place.
Except that's not the issue for long-term immunity. Long-term immunity is about building an immune memory, which is dependent on which immune pathway is primarily activated while fighting off an infection. Research on other coronavirus infections has suggested that the part of the immune system required to build long-term immune memory is not strongly activated by infection, hence the waning immunity in a matter of months. You see this with other illnesses too: it explains why you need boosters for some vaccines when you're a child, or periodic boosters as an adult, and why vaccines are not a trivial thing to make (eg, why we can't just inject someone with the virus particles and call it a day).
 
  • Like
Reactions: pmv

CZroe

Lifer
Jun 24, 2001
24,195
857
126
Except that's not the issue for long-term immunity. Long-term immunity is about building an immune memory, which is dependent on which immune pathway is primarily activated while fighting off an infection. Research on other coronavirus infections has suggested that the part of the immune system required to build long-term immune memory is not strongly activated by infection, hence the waning immunity in a matter of months. You see this with other illnesses too: it explains why you need boosters for some vaccines when you're a child, or periodic boosters as an adult, and why vaccines are not a trivial thing to make (eg, why we can't just inject someone with the virus particles and call it a day).
They didn't say "no evidence of long-term immunity." No one ever assumed there was. They said there was no evidence of any antibody immunity specifically to downplay the serological treatments (antibody extraction). If that were the case I think we'd know about it by now.
 

Ichinisan

Lifer
Oct 9, 2002
28,298
1,235
136
They eat bats in China and other parts of Asia, including pangolins and snakes. Supposedly thats how people flaunt their wealth by eating exotic meats when poor people can only afford pork.

...
The reason doesn't have anything to do with wealth flexing. It's "traditional Chinese medicine" bullshit. TCM is pervasive throughout China. They believe you need to eat specific animals or parts of animals to cure specific ailments. Often they say it should be eaten raw. The government and medical professionals even endorse stuff like bear bile. They actually farm bears for bile! It's basically the same idea as "snake oil."
 

killster1

Banned
Mar 15, 2007
6,205
475
126
The reason doesn't have anything to do with wealth flexing. It's "traditional Chinese medicine" bullshit. TCM is pervasive throughout China. They believe you need to eat specific animals or parts of animals to cure specific ailments. Often they say it should be eaten raw. The government and medical professionals even endorse stuff like bear bile. They actually farm bears for bile! It's basically the same idea as "snake oil."
bear bile is good for you! Ursodeoxycholic_acid its not snake oil. idk about curing covid because i havnt tried it yet :p doesnt sound like it will work but prob wont hurt your recovery hah