680SLI already creams 2560x1600, 7970GE CF does even more so. One of these single 'Titan' cards will come up short for that resolution, you'll still need two, at which point you'll be over the mark on what you need. I think a single Titan will have a lot of relevance for 1080P by finally delivering a single GPU that handles everything @ 1080P. Of course it is not going to be a card hardly any typical 1080P gamer will buy.
Two of them will wind up being overkill for 2560x1600/1440 as crazy as that sounds. You'll need SGSSAA or triple monitors to get them to flex their muscle.
Nvidia could be on to this as well. AMD/nvidia have to be waking up to the fact there is too much GPU power at this point with no games to push them. So we get $500 300mm2 dies with meagre performance increases and $900 low volume flagships that used to be $500 in the past. Probably makes a lot more sense to go this way. Take the have to have the best regardless of cost segment to the cleaners with 80% mark-ups in the form of $900 flagships and keep selling GK104 for $500.
This card could release just with the 'Titan' moniker and no other iterations of it with the GK104 continued to be sold as is.
I think that is the most likely scenario here if this price point is accurate.