The bugs can be funny, but they can also be annoying. I took a job from the Jarl of Markarth to clear out a dragon. No biggie. Snuck up on it, it saw me, and we started our little game of death. We exchanged blows, and all was going swimmingly... until I blasted it with a shock spell and it shot hundreds of yards into the sky. OK, that's odd.... I'll wait til he lands. No dice; he was permanently stuck a mile in the sky above the map (the icon would show up there and everything). And it left me with a quest that can never be completed because the dragon is no longer part of this material plane. Bummer.
I lost Shadowmere because I spawned on the Bard's Leap Summit and went over the edge, and the horse decided it was a good idea to follow me. He never respawned.
I've had to use the console a bunch of times to advance quest stages or remove inventory items that were never properly taken out when a quest was completed. I'm on my second playthrough and I've already had quest issues prevent me from advancing in The Golden Claw or Blood on the Ice. Lydia decided that she was going to stop following me in the middle of fast traveling and I randomly ran into her in the wilderness outside Falkreath (carrying a bunch of expensive shit I wanted to sell). I'm onto Elder Knowledge on my second playthrough and I figured I'd do the optional quest that involves talking to Esbern, but he's more interested in hitting dummies with a sword and refuses to talk to me. The game's a little bit silly with all the random bugs.... And yet it's still damned addicting, which is a testament to just how compelling it is.