2nd monitor seems to work the same way as in the first game. click in the first monitor, and your mouse controls the camera there. click in the 2nd, and you can set it to whatever view you want. I usually leave #2 at strategic view so i can monitor intel. if you try to track a unit, it always tracks on the main monitor. you can then issue commands on #2 if you like, but the OSD stays on monitor #1 so it is a little annoying if you want to track on one monitor and control on another. maybe they'll fix this if enough people ask for it. probably wouldn't be hard to fix as a UI mod.
also, that 60fps at the beginning of the game went down to 40-45 towards the end of the final mission with ~500 units on the map. never a hiccup...i'm really impressed performance wise.
i also really like the new research system. wish that one research station gained points faster though, i end up making 8+ research stations.
also the early economy is much easier. didn't run into mass or energy shortages nearly as easily. no dreaded game killing resource stalls. economy seems to be much less of a factor than in SC/FA