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Scientists discover Serotonin not found to be a major player in depression

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disappoint said:
It's not surprising that people want an easy way out of their depression. What easier way than to gobble a little pill?

But the easy way isn't usually the best or most effective way.

Most depression is caused by someone's expectations of their life exceeding the reality they find themselves in.

There are 2 ways to solve this. Change the reality or change your expectations. Maybe a little of both.

Take a little pill? If only it were that easy.
__________________
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you don`t know squat about depression...
 
Ok ok you can just take a pill to cure depression...

No need for therapy.

Oh except this latest study says 60-70% still suffer from depression after being put on SSRIs.

Yeah and I'm the one that doesn't know fuck all.
 
TheVrolok said:
Interesting findings, but single small study here. Let's all calm down.
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Some years ago I was following all this and the conclusion on the part of many was that SSRI's worked but not by the supposed mechanism. This is hardly unique as theory often lags proven biology. NSAIDS and theophylline would be examples. Naturally we'll hear "big pharma" and "the medical establishment" and whatnot, but those will probably be the same people who don't understand the physiology of obesity or sleep.

It is also demonstrative of a certain herd mentality where "the medical establishment" does latch onto things which have a basis in science but "common knowledge", a dangerous thing, creates a bias towards a preferred but sometimes erroneous consensus. In this case I'm thinking of cholesterol. There's a story by one of the primary investigators who was instrumental in determining that high serum cholesterol was a major factor in cardiovascular disease that I found amusing. He attended a conference of medical types who were talking about this new exciting discovery that eating eggs and food which had cholesterol were very bad for you. Our researcher (who's name escapes me for the moment) attempted to correct them since it was cholesterol in the blood which was the subject of his study, and they promptly looked at him like he was an idiot, citing his own research as "evidence" against him 😀

Anyway, that's an aside, but it does demonstrate that in medicine (and other fields of science- no one has the right to throw stones) nothing is "pure knowledge". Everyone has baggage but that does not mean that there isn't a factual basis. SSRI's even if misnamed will help some.
 
disappoint said:
Ok ok you can just take a pill to cure depression...

No need for therapy.

Oh except this latest study says 60-70% still suffer from depression after being put on SSRIs.

Yeah and I'm the one that doesn't know fuck all.
Click to expand...

Yes you don't know, well much of anything. Not about the nature of depression or treatment. Hey did you know that not 100% of people on chemo are cured of cancer? Well hells bells why bother?

To turn your statistic around 30 to 40% of people with depression are "cured". If someone came up with a cure for diabetes with that success rate someone would win a Nobel prize. Yes therapy perhaps with medication is better than pills alone but not everyone can/will do that and people in the field already know that. Your alternative for them is a zero chance. Not acceptable.
 
Hayabusa Rider said:
Yes you don't know, well much of anything. Not about the nature of depression or treatment. Hey did you know that not 100% of people on chemo are cured of cancer? Well hells bells why bother?

To turn your statistic around 30 to 40% of people with depression are "cured". If someone came up with a cure for diabetes with that success rate someone would win a Nobel prize. Yes therapy perhaps with medication is better than pills alone but not everyone can/will do that and people in the field already know that. Your alternative for them is a zero chance. Not acceptable.
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If you really think I don't know much of anything, then you don't know much of anything about me.

My statistic? It's not mine it's from the article. I didn't write the article so it's not on me if it's wrong or misleading.

My alternative for them is a zero chance? Where did I ever say they shouldn't take meds if it works for them? All I intended to state was that meds alone is not as effective as meds with therapy. If what I posted causes one person to seek more effective treatment than meds alone then it was worth it.
 
moonbogg said:
Anything that 350 million people have cannot be a disorder. Its too common to be a disorder. Its called being human, and why people expect their brains to function in unnatural ways is pretty odd.
Any tree that doesn't stay green year round has a disorder. Lets fix them all.
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Sure, I like your logic.
Almost everyone gets the flu once in a while, so it is no illness...
 
Mixolydian said:
I;ve always been skeptical of the "chemical imbalance" theory attributed to most mental health conditions.
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It depends. Schizos, FI, often can't function without changing that balance. Likewise, manic depressives.

OTOH, if your brain chemicals are out out of balance when you're depressed...well no shit Sherlock, you're depressed! Deal with what causes the depression, and your brain will right itself. But, if your brain is working like shit because you're short on serotonin (or dopamine, or something else), maybe SSRIs, or other drugs that alter various chemical levels in your brain, can help the other steps work.

Oldgamer said:
I wonder if you are right about the "tin foil" folks and the possible link between some people having an adverse reaction to SSRI's and anger outbursts or lack of control? Interesting..
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It's not tin foil at all, and is a point made on major MSM news networks, nowadays, every time we have yet another mass killing. Some of the mood- and judgment-related side effects, in lesser degrees, are right on the package. Long-term use of those drugs is usually a sign that somebody (parent or doctor?) is likely not acting in the best interests of that person, and there usually are multiple actors in that position, since all it would take is a doctor, parent, or the person in question, to realize that, and make relevant changes.
 
disappoint said:
I know right? Isn't it hilarious how these trolls come in and just post "You don't know fuck all" while saying nothing about the issue themselves?

Sounds like they are lashing out. Up the meds kids! LMAO
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I don't think you know what a troll is either.
 
disappoint said:
Ok ok you can just take a pill to cure depression...

No need for therapy.

Oh except this latest study says 60-70% still suffer from depression after being put on SSRIs.

Yeah and I'm the one that doesn't know fuck all.
Click to expand...

You don't know fuck all because no psychiatrist worth 2 shits will tell you that you can just "take a pill to cure depression", yet it seems to be your opinion that they all promote that.
 
irishScott said:
You don't know fuck all because no psychiatrist worth 2 shits will tell you that you can just "take a pill to cure depression", yet it seems to be your opinion that they all promote that.
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Suuure, no doctor has ever prescribed antidepressants without therapy.🙄
 
Headline: 1 in 10 Americans Use Antidepressants Most Don't See a Therapist:
http://abcnews.go.com/Health/Wellness/10-americans-antidepressants-therapist/story?id=14763251

Headline 2:
Why a Great Therapist Probably Beats a Great Antidepressant

Counseling is often more effective than a drug when it comes to easing depression, but what kind of psychotherapy should you choose to feel better faster? http://www.takepart.com/article/2013/05/24/best-therapy-for-depression-counseling-or-antidepressant

What is it about some of you that makes you resort to insulting someone by saying they "don't know fuck all"? Does it make you temporarily feel superior? Does that alleviate your depression? So it's a coping mechanism? It makes you seem desperate and unprofessional.
 
disappoint said:
Headline: 1 in 10 Americans Use Antidepressants Most Don't See a Therapist:
http://abcnews.go.com/Health/Wellness/10-americans-antidepressants-therapist/story?id=14763251

Headline 2:
Why a Great Therapist Probably Beats a Great Antidepressant

Counseling is often more effective than a drug when it comes to easing depression, but what kind of psychotherapy should you choose to feel better faster? http://www.takepart.com/article/2013/05/24/best-therapy-for-depression-counseling-or-antidepressant

What is it about some of you that makes you resort to insulting someone by saying they "don't know fuck all"? Does it make you temporarily feel superior? Does that alleviate your depression? So it's a coping mechanism? It makes you seem desperate and unprofessional.
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Well speaking as someone who actually was depressed for the better part of a decade and has been free of it for several years, I went through 4 different therapists and if anything they were reluctant to prescribe medication. Other depressed people I met through support groups voiced similar experiences for the most part.

And yes, counseling is often more effective than drugs long-term, I never claimed anything to the contrary. I also never said anything about GPs. As I said, I think you need to learn how to logic. A supplementary course in reading comprehension could also be of use.

If some GPs who don't know any better are prescribing antidepressants without treatment, then perhaps people trusting their GPs to treat them for depression should get their heads out of their asses. You don't see a GP when you have cancer, you see an oncologist. Likewise if your GP thinks you should be on antidepressants, it should be 1+1=2 that you should see a psychiatrist. Perhaps some reform is needed on the doctor's side of the fence, but any patient who's been through intensive treatment for any serious medical condition will tell you that the patient must take charge of their treatment to get the maximum benefit. Doctors often simply cannot refer you to magical cure heaven for anything that doesn't have a textbook cure, they often don't have the specialized knowledge or connections to anyone who does.

And as to your original point, claiming that most depression is "caused by a difference between expectations and reality" is simply false and has no basis whatsoever.

And take a good, sober look at your latest post. You're hardly one to call people out on being desperate and unprofessional.
 
disappoint said:
If you really think I don't know much of anything, then you don't know much of anything about me.

My statistic? It's not mine it's from the article. I didn't write the article so it's not on me if it's wrong or misleading.

My alternative for them is a zero chance? Where did I ever say they shouldn't take meds if it works for them? All I intended to state was that meds alone is not as effective as meds with therapy. If what I posted causes one person to seek more effective treatment than meds alone then it was worth it.
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What you intend and what you say are not always the same. Nothing cures depression. Nothing. It may persist, spontaneously remit or regress. In some individuals it doesn't reoccur, but if one suffers from depression they have a distinctly higher chance of having it happen again than someone who never did. No one who has an accurate, if elementary, understanding of the disease thinks a pill will cure. You keep bringing up therapy and therapy is desirable but despite anything else many people do not get it. That may be due to money, time, availability, stigma, whatever, but it is a widely recognized fact. In that case it is drugs or nothing.

As far as knowing nothing about the disease

Depression is sometimes caused by someone's expectations of their life exceeding the reality they find themselves in.

There are 2 ways to solve this. Change the reality or change your expectations. Maybe a little of both.
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What? No it's not, or at least a rare case. You zeroed in on a trivial possibility. There are trigger events that precipitate and event, but not always. The science shows that there's a considerable biological component here. If one twin who is separated at birth has an episode of depression there's about a 70% chance the other will too. I'm sure there's someone who has depression about life expectations, but I'm not sure you understand what depression isn't. It's not sadness or remorse or regret for what might have been. It's a clinical disease and it often can be treated, but the stigma associated with a failing of choice "change reality or expectations" isn't useful. Quite the contrary.
 
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disappoint said:
It's not surprising that people want an easy way out of their depression. What easier way than to gobble a little pill?

But the easy way isn't usually the best or most effective way.

Depression is sometimes caused by someone's expectations of their life exceeding the reality they find themselves in.

There are 2 ways to solve this. Change the reality or change your expectations. Maybe a little of both.

Take a little pill? If only it were that easy.
Click to expand...

i'm sure there are plenty of cases where people are truly depressed and anti-depressants make a massive difference in their life.

given that something like 10% of people in the US take some sort of anti depressant (just google it), i'm inclined to believe that depression is also overdiagnosed. 10% is a massive figure. I would expect any condition (mental, physical, medical) to represent a much smaller fraction of the population.
 
suffered with depression for alot of years...

tryed the SSRI's......fucking horrible withdrawal.


you know what works? opiates/benzos/pot/amphetamines

you know why?

dopamine.
 
ecstasy hangovers, is more about exhaustion/dehydration than anything serotonin related....


roll on E for 2 days straight.....feel like shit......do some amphetamines/meth...you'r right back on cloud nine..... it aint the serotonin.
 
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