Scientists discover Serotonin not found to be a major player in depression

[zanejohnson]

really they should just script people with depression 60mg hydrocodone a day...

i promise nobodys gonna be depressed.

 

[moonbogg]

Can you smoke Prozac? I think i'll stuff some in my E-cig and give it a go.

 

[disappoint]

suffered with depression for alot of years...

tryed the SSRI's......fucking horrible withdrawal.


you know what works? opiates/benzos/pot/amphetamines

you know why?

dopamine.

I know no one, including you, is going to take that seriously, but just for the sake of argument...

What happens when you build a tolerance to more and more dopamine? How about serotonin?

 

[disappoint]

What? No it's not, or at least a rare case.

You zeroed in on a trivial possibility. There are trigger events that precipitate and event, but not always.

Do you have any data or evidence to back that up? I was under the impression it happened more often than "rarely". If that even matters.

School shootings for example are rare. Try telling the parents who lost loved ones in those tragedies that it doesn't matter because it's rare. It matters to them.

I'm not convinced it is, but so what if the case I chose to talk about is rare? If there is someone out there going through it, it doesn't matter if it's rare. They just want to get better. To do that they first need to identify the problem.

The science shows that there's a considerable biological component here. If one twin who is separated at birth has an episode of depression there's about a 70% chance the other will too.

That depends on the cause. Actually it depends on a lot of things. Too many to list here. Which is why it doesn't even matter. What matters is getting people better. For that they need individual counseling with a qualified therapist. Not just chemicals thrown at a proverbial wall to see what sticks.

I'm sure there's someone who has depression about life expectations, but I'm not sure you understand what depression isn't. It's not sadness or remorse or regret for what might have been.

That much is obvious. Is there something about what I posted that leads people to believe otherwise?

It's a clinical disease and it often can be treated, but the stigma associated with a failing of choice "change reality or expectations" isn't useful. Quite the contrary.

Stigma? I think I'm starting to see why the backlash to what I've posted so far has occurred.

Do you feel as if I'm blaming the victim? As if the depressed person's own choices are at fault for their illness? That might sometimes be the case and sometimes not. Again each person needs to be evaluated for the actual causes of their illness.

The problem here is if you give those people reason to stay in denial, they will. It's always easier to do so. But they won't be helped by that. Heck they might even take your side and thank you for sticking up for their point of view against the evil disappoint boogie man that wants them to face reality rather than cozy up to the security blanket of denial.

 

[Black Octagon]

That website in the op really seems like shit. They go into great detail on how they want their article referenced, but don't even bother to reference the actual study they're talking about.

Here's the abstract to the study: http://pubs.acs.org/doi/abs/10.1021/cn500096g

I know right? Shame you and I are the only ones here who seem to notice or care about such details.

One might also point out that that abstract gives little/no information about the study methodology. So unless we actually purchase, read and (gasp) understand what the authors were doing, we just have to blindly accept that the study was unimpeachable and that the authors' conclusions were worth the proverbial paper on which they were printed.

(Remembers he's on an internet forum)

OmgItotallyknewit! Dang drug companies and corrupt shrinks! Imma go flush my meds and show 'em all.

 

[OverVolt]

I don't understand drug addicts. Saw some youtube video where a guy was ranting that normal people have a happiness of say, 100. So if they take a drug it goes to 120... and comes back down to 100. Its like... yea that was great and all but... meh. Drug addicts are likely unhappy and say they are sitting around 50 happiness with life, they take a drug and their happiness goes to 90, its like... holy shit I'm almost normal! Then it drops back down to 50. You never fix whats making you unhappy though. And you just develop dependence.

I have endorphin rushes without drugs! Crazy right. Like when I"m exhausted from work and something is funny even though it wouldn't be so funny if i wasn't so tired and I'll get a rush of natural endorphins from laughing/being overworked, almost like a runners high I suppose. I'll get it listening to the radio when a song I like plays even though I'm stuck in traffic commuting to my job. I can pretty much get one on demand by thinking about happy memories, music videos that I like, a funny joke a friend said... etc.

 

[disappoint]

I don't understand drug addicts. Saw some youtube video where a guy was ranting that normal people have a happiness of say, 100. So if they take a drug it goes to 120... and comes back down to 100. Its like... yea that was great and all but... meh. Drug addicts are likely unhappy and say they are sitting around 50 happiness with life, they take a drug and their happiness goes to 90, its like... holy shit I'm almost normal! Then it drops back down to 50. You never fix whats making you unhappy though. And you just develop dependence.

I have endorphin rushes without drugs! Crazy right. Like when I"m exhausted from work and something is funny even though it wouldn't be so funny if i wasn't so tired and I'll get a rush of natural endorphins from laughing/being overworked, almost like a runners high I suppose. I'll get it listening to the radio when a song I like plays even though I'm stuck in traffic commuting to my job. I can pretty much get one on demand by thinking about happy memories, music videos that I like, a funny joke a friend said... etc.

Drug addiction is simple to understand. They elevate their neurotransmitters and feel better than ever. Soon they will become dependent because they build a tolerance. That is to say the brain adjusts to the feeling until they have to "get high" just to feel normal again. If they don't they feel sick. What feels like 100% to you feels like 50% to them. In severe cases their brain literally feels like it's dying. That's called withdrawal symptoms.

All they really have to do to kick the habit is stop long enough for the brain to adjust to 100% feeling like 100% again. Not so easy when they feel sick slowly going from 50% to 100%, or maybe lower than 50%. Or just not start in the first place. Sometimes something else in their life drives them to doing drugs in the first place. Sometimes it's emotional.

Therapy can help with that.

Most people don't realize just how much of what they do has a subconscious origin. Sometimes when you tell them, they subconsciously fight it, like you see in this thread. See the anger from some of the posters in here? Most have no idea why they got so angry. These depressed folks get tired of depression, so they turn it into anger. When they get angry, they feel more in control, even if they really aren't. The subconscious doesn't know the difference between reality and fantasy, and it doesn't care. It gets it's "jollies" the easy way out, it just makes stuff up. It's a lot easier to "make stuff up" than really make it happen consciously.

Why do you think people turn to fiction so often to unwind? Of course you know why: it's easier than dealing with reality all the time. Dealing with reality all the time, I mean all the time: 24/7, would for certain drive you completely insane. You'd turn into a blithering idiot at first, then, maybe worse. This is why we need to sleep. The body needs it's rest to repair, as does the mind. But you can rest your body without going unconscious. Why not the mind?

 

[tesher]

The truth is that little is really known about detailed workings of the brain and it's associated problems.

 

[OverVolt]

The truth is that little is really known about detailed workings of the brain and it's associated problems.

Here try this drug.... no wait... how about this one? no..... okay *furrows eyebrow* this one will do ththe trick! no? well shit. Lets try a different approach..... a slightly different class of the same drug here ya go! I see your survey scores are slightly better.... great success!