NON_POLITICAL China Coronavirus THREAD

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Mai72

Mai72

Lifer
Sep 12, 2012
11,562
1,742
126
s0me0nesmind1 said:
@K1052

Here's some news you're gonna love.

Russia has a vaccine that haven't gone through any real clinical trials (that I'm aware of). They plan to massively produce + distribute it worldwide as soon as possible.

Click to expand...

Imagine if the vaccine turns people into zombies? :(
 
purbeast0

purbeast0

No Lifer
Sep 13, 2001
53,757
6,635
126
PingSpike said:
Even if the "kids don't spread it" study is correct...that study was only for kids under 10 wasn't it? I guess that was magically extrapolated to middle and high school kids because legally they're all children and viruses abide by man's laws.
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There is a special thing that happens to a child's body at midnight on their 10th birthday apparently.
 
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Svnla

Svnla

Lifer
Nov 10, 2003
17,986
1,388
126
More potential casualties of the virus. This fall, if college football is on hold or canceled (Pac12 and Big10), then many businesses near the stadiums could go down under/belly up.
 
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brianmanahan

brianmanahan

Lifer
Sep 2, 2006
24,687
6,049
136
ponyo said:
Who shops at Stein mart? This virus is just speeding up and putting businesses that needed to die out of their misery. It's like great forest fire. From the ashes the new forest will grow. It's ultimately healthy.
Click to expand...

i didn't even know it existed until january, had never seen one before
 
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A

Ajay

Lifer
Jan 8, 2001
16,094
8,116
136
K1052 said:
Yes, the data they released was sort of underwhelming even though some people showed an immune response. From what I have read part of the skill in making an adenovirus vector vaccine is picking a virus that hasn't been widely seen by people's immune systems already. This is likely the issue with their vaccine, the vector is getting beat by the immune system before it can get to the cells and start antigen production. Oxford solved this by using a chimp adenovirus basically guaranteed to be unknown to human immune systems.
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Yeah, at this point, Moderna seems to be a poor bet. I do wonder how low the FDA will set the bar for efficacy. I hope it’s at least 50%. Obviously, it would be better if we find a vaccine with a higher efficacy rate.
 
K1052

K1052

Elite Member
Aug 21, 2003
53,833
48,564
136
Ajay said:
Yeah, at this point, Moderna seems to be a poor bet. I do wonder how low the FDA will set the bar for efficacy. I hope it’s at least 50%. Obviously, it would be better if we find a vaccine with a higher efficacy rate.
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The FDA bar for licensing is 50% efficacy which is measured by reduction in disease severity or infection. Moderna's results so far seem likely to clear the reduction requirement, nobody is sure about the latter until we get more data.

My personal opinion is the most and perhaps all the vaccine candidates in advanced US trial will actually work to one degree or another. This virus isn't particularly crafty by any means when it comes to generating an immune response against it. The bigger question is what works best with the least side effects and the greatest protective factor. That's not to say I would not take a vaccine that eliminated the disease impact on my body while still allowing some level of infection, some vaccines already work like this. For first generation vaccine(s) pretty ok is going to be good enough for now.
 
Scarpozzi

Scarpozzi

Lifer
Jun 13, 2000
26,392
1,780
126
ponyo said:
Who shops at Stein mart? This virus is just speeding up and putting businesses that needed to die out of their misery. It's like great forest fire. From the ashes the new forest will grow. It's ultimately healthy.
Click to expand...
Steinmart here has a nice mix of affordable golf shirts and outdoors apparel for guys, maybe in their 50's-60's... I actually bought some decent beach shirts and a few decent blazers/jackets from there for $20 and less.

As far as their home section and female stuff...much of what they have in inventory is pretty stale. I'm not surprised that they're struggling. There's tons of competition in that space and their target market hasn't been shopping much this year.
 
Muse

Muse

Lifer
Jul 11, 2001
41,336
10,461
136
Ajay said:
Yeah, at this point, Moderna seems to be a poor bet. I do wonder how low the FDA will set the bar for efficacy. I hope it’s at least 50%. Obviously, it would be better if we find a vaccine with a higher efficacy rate.
Click to expand...
Think I heard last day or two on TV news that the Trump administration just paid Moderna $100,000,000 for their vaccine. :rolleyes:
 
D

[DHT]Osiris

Lifer
Dec 15, 2015
17,563
16,921
146
ponyo said:
Who shops at Stein mart? This virus is just speeding up and putting businesses that needed to die out of their misery. It's like great forest fire. From the ashes the new forest will grow. It's ultimately healthy.
Click to expand...
My MIL and her sister/niece used to go to Steinmart like twice a week, it was really more of a social visit thing, buy some cheap shit scarves or hats or whatever while chatting it up. I don't know of anyone that seriously said 'man, I need some clothes, let me find the shittiest ones possible'.
 
A

Ajay

Lifer
Jan 8, 2001
16,094
8,116
136
K1052 said:
The FDA bar for licensing is 50% efficacy which is measured by reduction in disease severity or infection. Moderna's results so far seem likely to clear the reduction requirement, nobody is sure about the latter until we get more data.

My personal opinion is the most and perhaps all the vaccine candidates in advanced US trial will actually work to one degree or another. This virus isn't particularly crafty by any means when it comes to generating an immune response against it. The bigger question is what works best with the least side effects and the greatest protective factor. That's not to say I would not take a vaccine that eliminated the disease impact on my body while still allowing some level of infection, some vaccines already work like this. For first generation vaccine(s) pretty ok is going to be good enough for now.
Click to expand...
Well, glad that the min requirement is 50%, even if that includes reduction of symptoms (if significant enough). The side effects issue will be limited in scope because of the accelerated Phase III testing schedule. We'll know immediate side effects, but not longer term issues that can be sussed out with the typical vaccine that take much longer to develop and spend more time in test. Guess this is a time when excellence is the enemy of the good.
 
thestrangebrew1

thestrangebrew1

Diamond Member
Dec 7, 2011
4,178
830
126
Muse said:
Think I heard last day or two on TV news that the Trump administration just paid Moderna $100,000,000 for their vaccine. :rolleyes:
Click to expand...

Yea I thought the gov just purchased a bunch of their vaccines. I was wondering if they would request a refund or maybe change the deal to get less vaccines and save a little. Prob not though.
 
K1052

K1052

Elite Member
Aug 21, 2003
53,833
48,564
136
Ajay said:
Well, glad that the min requirement is 50%, even if that includes reduction of symptoms (if significant enough). The side effects issue will be limited in scope because of the accelerated Phase III testing schedule. We'll know immediate side effects, but not longer term issues that can be sussed out with the typical vaccine that take much longer to develop and spend more time in test. Guess this is a time when excellence is the enemy of the good.
Click to expand...

I think the probability of long term adverse effects is pretty low. Certainly far less of a concern to me compared to the organ damage COVID patients are turning up with even if they are outwardly asymptomatic. The manufacturing blitz is something that should be watched more closely though since contaminated doses would be a disaster in many ways.
 
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K1052

K1052

Elite Member
Aug 21, 2003
53,833
48,564
136
thestrangebrew1 said:
Yea I thought the gov just purchased a bunch of their vaccines. I was wondering if they would request a refund or maybe change the deal to get less vaccines and save a little. Prob not though.
Click to expand...

Yes, the government bought 100M doses from Moderna. We've bought over half a billion total doses from 6 different manufacturers using three different platforms (adenovirus, RNA, subunit).
 
D

[DHT]Osiris

Lifer
Dec 15, 2015
17,563
16,921
146
K1052 said:
Yes, the government bought 100M doses from Moderna. We've bought over half a billion total doses from 6 different manufacturers using three different platforms (adenovirus, RNA, subunit).
Click to expand...
Should we be concerned that the US is trying to buy out the manufacturing capacity for these manufacturers to corner the market, as it were?
 
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