Well, I don't see it as 'resigning myself to that fate'. I'd literally be fine with working from home, buying supplies from the hardware store, growing my Sequoias, growing some vegetables, taking care of chickens and some goats (assuming my GF would let me have them), play some video games, watch netflix, and generally chill with my life until the day I die. That's not to say I wouldn't love to see more of the world than I've already seen, but even if I could afford it I would NOT, I repeat NOT unreasonably risk the life of myself, my GF, or other people for that. I don't care that much about seeing the fucking Library of Alexandria, much less some random fucking canyon in south Africa, or some dumb tower in some city.
Consider this, you might die if you get infected. You might die from an infection you got filling up with gas, because some asshat that has the same attitude as you pumped gas before you did, and HE was infected.
Society itself can absolutely withstand a limitation of global travel and a limited isolation to localized areas, we lived that way for about 20,000 years until airplanes were invented. I don't particularly give a shit if the dow crashes to 2k, and we all learn how to homestead again.
Honestly, we draw the line at whatever the government says we do. If enough people maintain the attitude that you have, the government will be FORCED to enforce a complete closure of everything, will quarantine all citizens, deliver food door to door, etc. That's an authoritarian hellscape but the government has a duty to preserve the lives of its citizens, and if its citizens are going to act like goddamn lemmings walking off a cliff, they're going to chain you to a tree so you can't wander off. It will happen, because they have the guns, and if you die you can't participate in the economy.