This game a took awhile to grow on me, but the more I play the more I enjoy it. I find it's a game that I sink a lot of time into at once or just do a few missions and come back later.
There are some really interesting side events that happen which I haven't seen done as organically as in this game. For example, a guy picked up a guitar and started signing an original song (to the game) and people from the camp started coming over to listen, slowly tap their feet or even dance a little. The song itself wasn't half bad and believable in the moment. Other random events are like that, but lose the special feel the 3rd or 4th time it happens.
As far as fuel, it's just something you keep an eye on, but has never become an issue besides the one time that the only gas can close got glitched for me. After awhile, you can fast travel to a spot near a gas station and then on to the next stop. Scrap, ammo and weapons are also abundant and are easy to manage. The shooting mechanic early on is pretty bad, but gets better with focus and higher quality weapons. I found that head shots in focus mode are the most efficient way to work, followed up by a strong melee weapon. Just keep enough scrap to repair as you fight. Also get used to the finger twister to heal while moving and dodging. I have gotten to the point where I use my right hand to heal on the left directional pad.
The story isn't too bad and Deacon is likable enough that you get past his quirks. Boozer feels like a drag at times, but I'm sure in that type of world, I'd keep any loyal friend no matter what.