how long 2.5" drives will remain available. Most modern laptops are thin enough that there simply isn't space available for a 2.5" drive in them.
It depends on the goals of the user more than the production value.
My laptops have space for 2.5's but, require brackets to add them to the mix. My current model is more high end though and deleted the space by adding a bracket to mount the M2's in the space provided. My prior laptop though had the M2's on one side of the case and a 2.5 on the other side for 3 drives total.
As things progress though and prices of M2 options come down the focus seems to move towards leveraging M2 as the preferred option since you can fit 2 of them in the same spaces as a 2.5 takes up. SATA being 600MB/s MAX vs up to 7GB/s gen4 it makes sense to move in the direction of speed as capacity should catch up eventually. As demand grows the prices come down for higher capacity drives.
For instance on the 8TB options a 2.5 runs about $137.50/TB on the M2 side but you get 5X the speed of a SATA equivalent but the SATA option / 2.5 8TB drives are just under $100/TB.
The only issue with larger capacities is that the speeds top out at gen3 ~3500MB?s as gen4 hasn't caught on yet that I've seen at this point. Not that anyone really needs those sort of speeds for what is more of a longer term storage application anyway. For immediate access devices i.e PS5 where the benchmark to use a drive is 5000MB/s per the built in self test.
It's an interesting time for growing pains across the board as tech advances faster than the product pipeline can keep up with. For instance I've been eyeing up adding Thunderbolt 4 as an option to the mix of things I play around with because it boosts the throughput for data from 16gbps to 32gbps by reducing the amount of reserved bandwidth for monitors / DP. TB4 has been out for a couple of years but, there's not much on the market on server or client side. Most products being rebranded for TB4/USB4 are using TB3 controllers and a USB switch that provides 10gbps. There's the niche 20gbps USB 3.2 2x2 option but, TB wants all or nothing and pushes it back to 10gbps for compatibility. I suppose this fall there's supposed to be more controllers coming out to boost speeds a bit in this arena. I did however just order a TB4 AIC for ~$50 off Amazon vs the retail price of ~$150-170 normally being charged. Seems people buy these things for systems that don't have the proper headers and then end up returning them or selling them because they can't figure out how to unlock the features. There's quite a bit of churn on them on Amazon though when a couple come in stock they sell right away or within a day or two.