The trailer sure has the Southpark episode feel. And while how meaningless this is to the game as a whole remains to be seen, I really wouldn't mind much with regards to the combat system or whatever, so long as the voices, jokes and story are properly "Southparkian".
But I agree with the above with regards to there being some hints at standard side-view RPG combat screens. Though the one scene with Kyle advancing into enemies with the golf club from close to an over-the-shoulder view could also be construed as a possible combat mode.
Maybe they're going for more of a mini-game based game like other cartoon/movie based games have done in the past. I remember some console Simpsons games, a good Die Hard game and at least one LOTR game that would change playstyle level by level. The idea has its merits, although it usually ends up in a "Jack of all trades, master of none" netherworld of mediocre gaming.
I find that it's actually pretty cool that with Southpark being made the way it is, and with technology being at the point where it is today; that we can realistically hope to be playing an epic episode like Go God Go, Imagination Land or Pandemic/Pandemic 2: The Startling in real time HD.
Unfortunately I doubt that this will be sufficiently ground breaking to have that actual show feel outside of cutscenes and such.
Still, with a strong script and story from the writers and an even mildly entertaining combat/item system, I really can't see myself passing this one up.
...
Heh heh, I wonder if the contract they had with Isaac Hayes would allow them to use previous recordings of Chef to throw the character in based on canned sound-bites. The show they did with fragments of previous recordings patched together to create his lines was comically halting, but in video game format, it really could work. Have a ghost, or zombie, or whatever, of Chef in there...
But I don't suppose that's at all likely to happen. Although Darth Chef works well enough and doesn't depend on Hayes being in good terms with them, or alive for that matter.