Here's my setup...
(TV+Sound)
65" HD Mitsubishi WS-65819
Klipsch Pro-Media 5.1s w/DD-5.1 Decoder
Klipsch 12" subwoofer KSW-12
Panasonic DVDRP82s - Monster cables linking everything
Audio Authority SP/DIF 4 port audio switch
(HTPC)
Skyhawk 4u IPC4032 Rackmount case
ASUS P4S8X - P4 2.12ghz (o/c 1.6a) - 512MB/DDR266 - Segate 40GB 7.2K + WD 200GB SE 8mb 7.2k HDs
16x Liteon DVDROM - SB 5.1 w/Drive I/O 2
ATI Radeon 8500LE 64mb
HiPix HD connected to TV with Audio Authority 9A60
CystalFontz 20x4 LCD
Logitech Cordless Freedom KB+optical mouse
Windows XP Pro SP1 running at 848x488 60hz (haven't had any luck getting anything but this res and some crazy high res @ 29hz that makes everything unreadable)
(Misc)
Playstation 2 connected with Monster component cable
Logitech wireless rumble pad
Even though the promedia's sound great, this setup is in my basement which is a pretty large room, so those little speakers have a hard time filling it... When I get some spare cash (not gonna be awhile since half the people in my house are doing temp jobs, or have seasonal jobs that haven't picked up yet) I'm going to get a better sound system... I love the way klipsch speakers sound so I will probably go with them and an HK/denon receiver...
Word to the unwise (like my stupid ass) don't play vice city with that damn radar turn on, I'm starting to get burn in on my hdtv from that ring

You can only really see it when that part of the screen is mostly a single bright color, but I know it is there and it drives me nuts...