Layoffs suck, but it's always been my understanding (based on anecdotal experience with an advisor-of-an-advisor that sold his company, and general talks with other biotech-aware professors) that pharmaceutical companies usually have the ultimate goal of being bought up by a big one, because it's the Pfizers and Mercks of the world that can shoulder the costs of actually getting a drug onto the market. It's usually the one drug that strikes gold that makes a company appealing to purchase, not their workforce. We don't live in a world where one goes through apprenticeship, gets close with the business owner, gradually working their way up until retirement in the same town 40 years later, moving around is part of how things work now.
My second sentence addressed your productivity question. If these hypothetical workers are really that productive, assuming they work in an industry that doesn't suffer from labor monopsony (e.g. Nike or Walmart where anyone with a pulse and four limbs can work), I don't see why they can't find work elsewhere.