Personally until I see how the granite bay mobos do and if they have only 1:1 ratio I would really want to stick with lower multiplier chips like the 2.4b or the 2.26b so I can fsb high as it can go.....
Ie...a lot of the 2.26b's are getting to around 2.8ghz and that means about 166fsb or 333mhz ddr in a GB dual ddr mobo....unless the 2.53's are getting 100mhz over the 3ghz mark and at current with no c stepping chips yet surfacing I know this isn't happening with any great frequency, I wouldn't take the chance