Here's the spot where they mention 53x multiplier:
I had a little trouble figuring out the context of this specific part of the video but it looks like:
One or more of the companies running Raptor Lake-S on W680 had problems with stability so they (when working with Wendel) settled on a few configs to mitigate that, and 53x with single DIMM configs were most stable, but still were crashy. And they're getting tray after tray of CPUs from Intel as replacements for ones that have failed to the point of being useless. So it appears as if these companies are (or at least were, as of Wendel's inquiries) taking new Raptor Lake-S CPUs, putting them in W680 motherboards, and running these settings, only for there still to be failures.
In other words maybe W680 CAN permit higher clocks under some circumstances, but for the purposes of Wendel's inquiries when testing systems with the cooperation of the game server provider companies, they settled on: 53x max multiplier, single DIMM config, disable HT, disable e-cores.