"Dear diary...Jackpot!"
Lois: For me? Please?
Peter: All right, all right, but you owe me. Later, under the mistletoe, open mouth, no matter how drunk I am.
Stewie: I needn't fear this Santa. If he were truly omnipotent he'd have the testicular fortitude to show himself!
Peter: The deep south? Isn't that the place where the black guys are really lazy and all the white guys are just as lazy but they're mad at the black guys for being so lazy?
Stewie: Oh, I feel so deliciously white trash. Mummy, I want a mullet!
Brian: Look over there! It's a newly married interracial gay couple burning the American flag!
Vacuum repairman: There you go, all fixed. Turns out a half-eaten meatball was clogging up the intake.
Peter: Oh. Well, did you save it?
Vacuum repairman: Uh, no.
Peter: You bastard.
<some spoof of that scene in american beauty plays where the guy is filming that bag blowing in the wind>
God: It's just some trash blowing in the wind! Do you have any idea how complicated your circulatory system is?!
<family is about to go to a baseball game and chris made a sign to bring along that reads "John 3:16">
Brian <opens a bible and reads the passage>: And the Lord said, Go Sox.
Chris: Dad, what the blow-hole for?
Peter: I'll tell you what it's not for, son. And when I do, you'll understand why I can never go back to Sea World.
Stewie: "Remind me to ask the doctor when my other testicle is going to descend."
Adam West:I love this job more than I love taffy... and I'm a man who enjoys his taffy.
Stewie: "Yea, and God said to Abraham, 'You will kill your son Isaac.' And Abraham said, 'I can't hear you, you'll have to speak into the microphone.' And God said, 'Oh, I'm sorry, is this better? Check, check, check. Jerry, pull the high end out, I'm still getting some hiss back here.'"