Working for a long time in a paramilitary (career fire department) environment, I often use them as a reflex adressing folks I don't know.
Several years ago I spent about two weeks in London. I was in a small bar in between Christmas and New Year's, just getting out of the place we were sharing with my wife's family. There were only handful of seats at the bar, a few tables, and otherwise standing room. I saw a guy who had 15 years or so on me walk through the door, scan the bar like he was looking for a seat, and pause seeing all the bar stools taken. Out of habit, I stood up, waved to him, and addressed him as "Sir" when I offered him my seat. I got a "fuck your sir, I work for a living" response. I was dumbfounded and started to backpedal explain that it's just a habit in my line of work as a firefighter.... He let me go for a few seconds, broke into a smile, offered his hand, and asked what I was drinking. I pointed to the tap setup and said I just had that one (a local British brew) but that I was really just looking to sample stuff I might not see in the US. Turns out he was also a local bartender nearby, and this was his hangout on his nights off. I guess an American tourist being polite, and not looking for a Budweiser struck him in the right mood. He treated me to several more rounds (I did buy a couple also), and told the bartender there to look after me for the rest of my trip (they did.)
TLDR sometimes it works....