Yes, definitely. Here are some of my faves (I almost never read mainstream Marvel/DC stuff):
The Walking Dead - Zombie survival story. It's by Robert Kirkman who did the Marvel Zombies mini-series you mentioned. It's in black and white and mostly seems to be in the style of the Romero classics.
Invincible - Also by Kirkman. The story of a highschool kid that starts getting superpowers and finds out his dad is Omni-Man (who's kind of like Superman). It sounds horribly lame and I avoided it for a long time because it sounded so formulaic, but it's really not. The stories are fantastic.
Top 10 - Imagine Law & Order or NYPD Blue, but set in a city full of robots, vampires, superheroes, Greek gods, wizards, telepaths, etc. etc. It gets a little too edgy sometimes -- the writer likes to deal with taboos like incest, pedophilia, bestiality, and the like. In that respect, it's really more like a Law & Order: SVU, but with more swearing.
Powers - Similar to Top 10, but darker, more in the style of Batman: The Animated Series (if you're familiar). And it only features superheroes and how they interact with a more realistic modern-day legal/enforcement system. The cops in this one don't have any powers themselves.
Y: The Last Man - Every male creature on earth dies except for one guy and his pet monkey. Society crumbles, then begins to rebuild. Vaguely post-apocalyptic.
If you look on Amazon, you can find the trade paperback versions of all of those -- they usually collect 6-12 issues in a single volume. None of these are aimed at (or appropriate for) children.