Those will work together. Are you upgrading your current system or building all new?
If upgrading you will also need a new PCI-E video card, the AGP card in your current rig won't work with that setup.
If your building new I would suggest considering an Intel core 2 duo setup, I have always been a huge AMD fan but they just can't currently compete with the C2D. And the E4300 can be had for just over $150
There are also a few boards that will allow you to reuse your DDR ram and AGP video card if your upgrading