I did this on the Intel side and it was a bit of a Cluster-F to deal with all of the moving targets on the HW side.
Thankfully for you AMD heads all of that has shaken out at this point with the biggest issue being DDR5 being scarce and forcing our hands to use DDR4 or pay the $300+ tax on the RAM / MOBO.
Looking for computer memory prices or hard-to-find memory modules? Maybe one of memory trackers can help.
www.nowinstock.net
There's nothing on the market right now though for PCI5 devices though they're likely to show up around the launches in Q3/Q4.
There's nothing wrong with jumping in head first at launch if you know what you're getting yourself into. I didn't have any issues with the build other than waiting on Linux kernel to update to include provisions for ADL / hybrid CPU instructions. Even without them enabled it still flies for processing files and performing as my all in one router/switch/firewall/NAS/DVR and a few other functions. I don't need a GPU though since it's a headless server so, can't really speak to that.
Switching to a LGA 1700 socket though threw a curveball into the cooler market though initially some were offering adapters for prior kits and some new products came out w/ a slight delay that didn't need to be rigged. There will be likely some slight fitment issues surrounding launch if vendors don't have proper pieces available.
The GPU / PSU thing though could get interesting with the higher output needed for some of the monsters being discussed being 900W and a different connector. I suspect there will be adapters that go inline on the GPU end to converge a couple of leads from the PSU in the new socket on the cards. There should be new PSU cables though to accommodate them around the same time as GPU releases though.
It's all a bit of speculation but, reasonable to expect things to come together around the same time.