The biggest problem I think I have is citizens not doing what they should. If I'm trying to build a hunting lodge, nobody will go there for like half a year, they're off carrying food or idling, literally ignoring me.
I also thing some of the stats get stuck. If I take out the wood cutter that stat, at least one time stayed stuck at the same number and now it's happening again with medicine. I made the herbalists and the number stays the same.
IT's wierd because everything was going fine, I had school with 5 students, hospital with doctor but no paintence, blacksmith, woodcutter, 3 fisheries, two hunting lodges and gathering and I was fine all through the last winter then come summer staving. I had about 8 people starve to death in the summer and hit winter with no food or wood... the game is fixed.
The only thing that I have found that needs fixed/adjusted is related to Feeding people. If you assign a task that's too far from their home, they'll get hungry and need to return all the way home before they can eat. Some kind of food carrying capacity or alternate building where they can eat is needed.
Things to keep in mind:
1) When you build a House, a certain amount of Food and Firewood will be transferred to it. If your storage of these is low, it could cause a shortage for others who don't live in that house
2) Some buildings, like Hunting lodges, Gatherers, others can take more than 1 Worker.
3) Resource buildings need to be located in the proper environment. Foresters/Gatherers in Forests, for eg
4) Avoid overlap in resource gathering between same buildings.
5) Build Barns/Stock piles near Resources to cut down on travel
6) Keep track of Resource limits, your workers will stop working once the limit is reached. That can be a serious problem once your population increases. Food/Fire wood, for eg should be set way above what you need.