Having used mine for a couple of weeks now, I still love it. My primary complaints are with Android and not with the hardware itself.
- Common Windows shortcut keys / key combos may or may not work. Ctrl+Z usually works, and Ctrl+C or Ctrl+V seem to work most of the time, but Ctrl+X, Ctrl+S, and Ctrl+A are a lot more spotty. It's a different OS (and one primary designed around touch input) so it's to be expected, but I love to see either Asus or Google step up to the plate with these to make Android an ever more viable switch for basic "netbook" tasks. Alt+Tab would be nice too - defaulting to the window-switcher application is a no-brainer (yes, I know there's a different shortcut button on the keyboard).
- The tap-to-click function of the touch pad doesn't always work. Actually clicking works every time, though. Two-finger scrolling works brilliantly.
- Android REALLY needs a simple window minimizing / closing system like the standard three buttons at the top right of every window in Windows. A standard "file" menu placement that all apps must adhere to (or at least, have to be specifically coded not to include, if they so choose) would be excellent as well.
- Saving a file that has been downloaded and transferring files from one place to another can be a major pain. Maybe I haven't found an option yet, but I'd really like to be able to specify where the file should be saved when I initiate a download.
Like I said, those are more software / Android complaints than they are TF101 complaints. Overall, I'm very impressed with the device, and I've started carrying it around as my day-to-day computer (due to the size, mainly) unless I absolutely need the power and flexibility of my notebook.