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Anyone ever been to India without a typhoid vaccination?

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Anonemous said:
I remember from that other thread to not even drink the residual tap water in your mouth when you brush your teeth.
Click to expand...

Even better brush your teeth with bottled water.

I spent three weeks in Northern India in October of last year. I did not get sick once. Stick to bottled water, and cooked food. You should be fine.
 
cyclistca said:
Even better brush your teeth with bottled water.

I spent three weeks in Northern India in October of last year. I did not get sick once. Stick to bottled water, and cooked food. You should be fine.
Click to expand...
Yep, brushed with bottled water last night. Am toying with the best way to disinfect and clean limes so I can eventually work out a gin and tonic. 😀
 
Many forms of arthritis can be successfully treated using the trace mineral boron.

Anyway... pardon my candor, but suppressing the immune system to ameliorate arthritis is almost as crazy giving people chemotherapy (basically cancer) in order to kill cancer. I personally would visit an immunologist who is smart enough to veto the trip, on doctor's orders.

david-vetter-bubble-boy-013.jpg


Ganges-River-Body-Pollution.jpg
 
bradley said:
Many forms of arthritis can be successfully treated using the trace mineral boron.

Anyway... pardon my candor, but suppressing the immune system to ameliorate arthritis is almost as crazy giving people chemotherapy (basically cancer) in order to kill cancer. I personally would visit an immunologist who is smart enough to veto the trip, on doctor's orders.
Click to expand...

Mm, you're not giving me a lot of reason to put faith in your medical wisdom here. Rheumatoid arthritis is when the body's immune system attacks the connective tissue in the joints. The most effective arthritis treatments are those which regulate the immune system to reduce that activity.
 
bradley said:
Many forms of arthritis can be successfully treated using the trace mineral boron.

Anyway... pardon my candor, but suppressing the immune system to ameliorate arthritis is almost as crazy giving people chemotherapy (basically cancer) in order to kill cancer. I personally would visit an immunologist who is smart enough to veto the trip, on doctor's orders.
Click to expand...

WTH? Chemotherapy is cancer? You might want to google/wikipedia that one. In one sentence, it's basically drugs/compounds used to target cells which grow fast (like cancer but has side effects on blood cells/hair/gut/etc since they also grow fast). You are basically poisoning the body in the hopes you can kill the cancer before the patient.
 
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AreaCode707 said:
Yep, brushed with bottled water last night. Am toying with the best way to disinfect and clean limes so I can eventually work out a gin and tonic. 😀
Click to expand...

I don't think you have to be that paranoid.

If you can get out of the office for a half day the surrounding countryside can be really nice. I forget the name but there's some hill with ruins that's not too far from town, get a great view of the countryside from up there. Hop on a bus and get a little local flavor.

I don't remember anything particularly interesting in Bangalore proper.. I guess the gov't buildings were kind of neat and grandiose.

edit: actually I take that back there were some cool markets.. wherever the beef butcher is was a cool market, really smelly with all kinds of meat hanging everywhere. Interesting place
 
Farang said:
I don't think you have to be that paranoid.

If you can get out of the office for a half day the surrounding countryside can be really nice. I forget the name but there's some hill with ruins that's not too far from town, get a great view of the countryside from up there. Hop on a bus and get a little local flavor.

I don't remember anything particularly interesting in Bangalore proper.. I guess the gov't buildings were kind of neat and grandiose.

edit: actually I take that back there were some cool markets.. wherever the beef butcher is was a cool market, really smelly with all kinds of meat hanging everywhere. Interesting place
Click to expand...

One of the colleagues that I'm traveling with is Indian and I think we'll spend an evening at a market at least, though a half day away isn't in the cards. 🙂
 
1. I went to Bangalore in a group of 3 about 16 months ago and none of us got immunized. We stayed in the Leela Palace which is a nice hotel so hygiene there wasn't an issue. It was bottled water everywhere...none of us got sick at all.

2. Bangalore isn't the best tourist spot but we enjoyed ourselves anyway. We took a hotel taxi to Nandi Hills the first day - it's a nice spot where you can see for miles due to its altitude and relative flatness of the surrounding area. There's also an ancient temple at the top which was interesting as well. The drive up the mountain was terrifying - driving in India is an adventure anyway and our driver constantly passed other cars around blind curves. I guess a couple of friendly honks is all it takes to stay safe.

3. We also saw the sultan's summer palace (moderately interesting), and several more temples.

Enjoy Bangalore, HC!
 
There are two different typhoid vaccines. The injectable is (probably) perfectly safe while on Enbrel. The oral one though...

Too late now, I know.
 
bradley said:
Many forms of arthritis can be successfully treated using the trace mineral boron.

Anyway... pardon my candor, but suppressing the immune system to ameliorate arthritis is almost as crazy giving people chemotherapy (basically cancer) in order to kill cancer. I personally would visit an immunologist who is smart enough to veto the trip, on doctor's orders.
Click to expand...

They are about equally crazy. If by that you mean "not crazy at all."
 
AreaCode707 said:
Yep, brushed with bottled water last night. Am toying with the best way to disinfect and clean limes so I can eventually work out a gin and tonic. 😀
Click to expand...

If you're really that paranoid, do this:

- boil water
- throw whole limes in water
- let boil for about 15 seconds
- drain water
- dry limes with paper towels
- cut limes, put into gin
- mix gin and tonic as needed

😛
 
Gibsons said:
They are about equally crazy. If by that you mean "not crazy at all."
Click to expand...

Most honest oncologists have read the numerous studies demonstrating that chemo can induce more cancer formation. For instance, a recent study made clear that healthy prostate cells were damaged by chemo and secreted WNT16B protein, therefore dramatically increasing cancer cell survival.


Nat Med. 2012 Sep;18(9):1359-68.
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.
Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, True L, Nelson PS.

Source: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Abstract: Acquired resistance to anticancer treatments is a substantial barrier to reducing the morbidity and mortality that is attributable to malignant tumors. Components of tissue microenvironments are recognized to profoundly influence cellular phenotypes, including susceptibilities to toxic insults. Using a genome-wide analysis of transcriptional responses to genotoxic stress induced by cancer therapeutics, we identified a spectrum of secreted proteins derived from the tumor microenvironment that includes the Wnt family member wingless-type MMTV integration site family member 16B (WNT16B). We determined that WNT16B expression is regulated by nuclear factor of κ light polypeptide gene enhancer in B cells 1 (NF-κB) after DNA damage and subsequently signals in a paracrine manner to activate the canonical Wnt program in tumor cells. The expression of WNT16B in the prostate tumor microenvironment attenuated the effects of cytotoxic chemotherapy in vivo, promoting tumor cell survival and disease progression. These results delineate a mechanism by which genotoxic therapies given in a cyclical manner can enhance subsequent treatment resistance through cell nonautonomous effects that are contributed by the tumor microenvironment.
 
bradley said:
Nat Med. 2012 Sep;18(9):1359-68.
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.
Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, True L, Nelson PS.

Source: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Abstract: Acquired resistance to anticancer treatments is a substantial barrier to reducing the morbidity and mortality that is attributable to malignant tumors. Components of tissue microenvironments are recognized to profoundly influence cellular phenotypes, including susceptibilities to toxic insults. Using a genome-wide analysis of transcriptional responses to genotoxic stress induced by cancer therapeutics, we identified a spectrum of secreted proteins derived from the tumor microenvironment that includes the Wnt family member wingless-type MMTV integration site family member 16B (WNT16B). We determined that WNT16B expression is regulated by nuclear factor of κ light polypeptide gene enhancer in B cells 1 (NF-κB) after DNA damage and subsequently signals in a paracrine manner to activate the canonical Wnt program in tumor cells. The expression of WNT16B in the prostate tumor microenvironment attenuated the effects of cytotoxic chemotherapy in vivo, promoting tumor cell survival and disease progression. These results delineate a mechanism by which genotoxic therapies given in a cyclical manner can enhance subsequent treatment resistance through cell nonautonomous effects that are contributed by the tumor microenvironment.
Click to expand...

Eh, of course drug resistance is a big problem in cancer treatment and some treatments are particularly effective for some forms of cancers while promoting the growth of others. In some cases chemo saves a majority of the patients but 30% relapse and develop resistance. A lot of this is not well understood but physicians have to make the call with whatever is the best treatment out there for saving the patient's life.
 
bradley said:
Most honest oncologists have read the numerous studies demonstrating that chemo can induce more cancer formation. For instance, a recent study made clear that healthy prostate cells were damaged by chemo and secreted WNT16B protein, therefore dramatically increasing cancer cell survival.


Nat Med. 2012 Sep;18(9):1359-68.
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.
Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, True L, Nelson PS.

Source: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Abstract: Acquired resistance to anticancer treatments is a substantial barrier to reducing the morbidity and mortality that is attributable to malignant tumors. Components of tissue microenvironments are recognized to profoundly influence cellular phenotypes, including susceptibilities to toxic insults. Using a genome-wide analysis of transcriptional responses to genotoxic stress induced by cancer therapeutics, we identified a spectrum of secreted proteins derived from the tumor microenvironment that includes the Wnt family member wingless-type MMTV integration site family member 16B (WNT16B). We determined that WNT16B expression is regulated by nuclear factor of κ light polypeptide gene enhancer in B cells 1 (NF-κB) after DNA damage and subsequently signals in a paracrine manner to activate the canonical Wnt program in tumor cells. The expression of WNT16B in the prostate tumor microenvironment attenuated the effects of cytotoxic chemotherapy in vivo, promoting tumor cell survival and disease progression. These results delineate a mechanism by which genotoxic therapies given in a cyclical manner can enhance subsequent treatment resistance through cell nonautonomous effects that are contributed by the tumor microenvironment.
Click to expand...

Is that the best you could find? Look up alkylating agents if you want to find some really nasty chemos. Here, search these: Ifosfamide, cisplatin, nitrosurea.

So, yes many chemotherapeutic agents are also carcinogens. Everyone knows this. The risk of carcinogenesis must be weighed against the therapeutic value of the drug. However, in many cases, these drugs are by far best, perhaps only, hope for survival of the patient. This fact usually outweighs an increased risk of cancer at a later date. This is a rational, calculated process, the opposite of "crazy."
 
Gibsons said:
Is that the best you could find? Look up alkylating agents if you want to find some really nasty chemos. Here, search these: Ifosfamide, cisplatin, nitrosurea.

So, yes many chemotherapeutic agents are also carcinogens. Everyone knows this. The risk of carcinogenesis must be weighed against the therapeutic value of the drug. However, in many cases, these drugs are by far best, perhaps only, hope for survival of the patient. This fact usually outweighs an increased risk of cancer at a later date. This is a rational, calculated process, the opposite of "crazy."
Click to expand...

You two, go start your own thread.
 
OP, while I haven't been to India yet but I did travel extensively to many countries in Asia. As a matter of fact, just did a trip to Asia recently.

You will just have to be careful with what you eat, drink, and daily activities then you will be fine. No tap water or ice from tap water. No meals from street vendors. Everything must be well cooked, no exception. Wear a mask or bandana to cover your face and nose from the air, a brim hat to protect your hair, long sleeve shirt to protect your arms from the sun./

Have a safe and fun trip. Take a lot of pictures.
 
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Gibsons said:
Is that the best you could find? Look up alkylating agents if you want to find some really nasty chemos. Here, search these: Ifosfamide, cisplatin, nitrosurea.

So, yes many chemotherapeutic agents are also carcinogens. Everyone knows this. The risk of carcinogenesis must be weighed against the therapeutic value of the drug. However, in many cases, these drugs are by far best, perhaps only, hope for survival of the patient. This fact usually outweighs an increased risk of cancer at a later date. This is a rational, calculated process, the opposite of "crazy."
Click to expand...

Some cancer drugs are particularly nasty, including IAP antagonists, but who needs healthy bones anyway.

Emerging cancer drugs may drive bone tumors
Washington University School of Medicine in St. Louis
February 12, 2013
By Julia Evangelou Strait
http://news.wustl.edu/news/Pages/24916.aspx

"Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers at Washington University School of Medicine in St. Louis. "
 
I would not go to India if I weren't vaccinated.

But that's just me.

Heck, I probably wouldn't go to India even if I was.
 
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