Photoshop, now before I get flamed, photoshop is what alot of people use. It's actually not all that difficult, infact, I found it easier than PSP. The pricetag may be a turn-off, but if you can afford it, and plan to do any graphic work at all in the future, it's the way to go. It's something where you could learn, and then grow into the program, instead of growing out of it.