Jesus! I love spiders, but even that would freak me out.
Whenever I find one in the house I usually leave it be, or move it to a safer locale. In fact, this thread is rather topical: This evening, while watching a movie with my girlfriend, I noticed the little spider that has been living in my room for a few weeks. He was on the wall, just above her head. I asked her not to move, which immediately freaked her out. I picked him up and put him in the garage for the woman's sake.
It was tiny, but she still screamed when she saw it. If she had seen that spider under the clock she would never have set foot in my house again.