Do you know if Windows 7 allows you to swap hardware like the motherboard/CPU without reinstalling the OS? I think the motherboard I currently have is giving random issue for USB, video, etc. I may need to swap the motherboard.
Doing Sysprep will insure that all works good and windows doesn't crash on ya when you install the new hardware.
You will have to do the Windows Activation again once the new motherboard is installed.
Right Bonzai, a person could argue that the old motherboard died and he or she decided to do a major upgrade since needing to replace the motherboard anyhow.
Which as the OP states, "I think the motherboard I currently have is giving random issue for USB, video, etc." Makes that argument pretty much truth.