Some points:
1) Wikipedia rocks!
http://en.wikipedia.org/wiki/Windows_Vista (links to Readydrive and more)
2) I don't recommend using any current memory cards for boosting speeds. However, memory card speed will overtake hard drive speeds so this function will become more useful in the future.
3) 2GB of RAM is recommended for any serious gamer and/or multitasker but most will be happy with 1GB.
4) 4GB of RAM may actually slow down your PC slightly depending on your motherboard, other hardware and usage
5) future RAM will be non-volatile. It is expected that Windows will sit on non-volatile RAM. If non-volatile RAM can be made quick enough, it is likely that volatile RAM (needs power) will not be needed, especially in laptops where power usage is critical. (1GB of memory takes between 10 and 20 Watts, but is dropping due to smaller transistor sizes (DDR2 uses less power at higher speeds than DDR), however non-volatile RAM uses NO POWER except for when it is being accessed which would average to a tiny fraction of 1Watt)
6) Hard drives will be around a long time still and Hybrid will become common, but hard drives will switch to storage only and eventually will fade away.
Note, high-speed, non-volatile memory is the Holy Grail. Most computer speed annoyances are hard-drive related. Current dual-core CPU's only need about 1% of their raw power to be involved in full-speed hard drive transfers of 60MB/s.
It is hoped that carbon nano-tubes or similar technology can replace the hard drive and main memory. It is believed that current hard drive speeds (mainstream about 60MB/s) could improve by several hundred times. Every task on such a system will appear almost instantaneous with the exception of tasks like video and audio compression which depend primarily on the CPU.
*Note that 120X speed (which all agree will easily be achieved in non-volatile RAM) any task limited by the hard drive (like cold-boot, tranferring files, opening programs) that normally takes two minutes will take ONE SECOND. This also represents the time to transfer the contents of a full DVD-Video of approximately 7GB.
This is the near future, and one which Microsoft Vista is making software arrangements to utilize. It is uncertain when the hard drive replacement breakthrough will occur but this will be the most important breakthrough as annoying wait times will be eliminated almost entirely. (also, defragging will probably still be done despite not being necessary but you'll never see it)