Are you kidding? No opprotunity to make a mistake that would kill someone? What if we design a navigational system for an aircraft that doesn't take into account that there's an equator and flips an airplane upsidedown while the people on board aren't strapped into their seat? Or how about we design a chip that overheats too easily under certain conditions and this chip is part of a crucial system?
By the way the airplane example was told to me by a professor of mine. He says it really happened with an actual plane, but I have no way of verify the truth.
Oh, yes, also while on my last co-op job, one of the computer engineers there found a flaw in a piece of software that had been there for a while, but no one noticed. It could have easily been exploited to kill a lot of people and cause a lot of damage had anyone looked hard enough.