the one where i can google up the answer to your problem in chrome as going into settings and setting the default global zoom..
seriously how many times a day do you flash a drive bios, if something is that broken fine, set the dpi back for a moment and then back when you are done, this stuff is easy now, you don't even have to dig through menus anymore,,just type dpi in the box..
I've tried it numerous times. I'm also adept and Ctrl+[+], Ctrl+[-], Ctrl+0, Ctrl+MouseWheel, ...
...also [WinKey]+[+], [WinKey]+[-], [WinKey]+[Esc].
Also, the zoom setting causes web pages to have some of the EXACT same issues that I described with Windows applications when DPI is increased.
Look at those tiny tabs!
...and, NO, you can't just change Windows DPI on-the-fly. It forces you to close ALL open applications and log-off.
...and it's not just BIOS flashing. It's installing applications, getting iPhone UDIDs from iTunes, and many, many, many other countless frustrations. I encounter DPI-related problems every day, no matter what DPI I set except the default DPI.
[edit]
Even this post is an example of Chrome's Zoom causing problems. The 1920x1200 screenshot I just made is 25% larger than the width of my monitor and the full image does not fit on my screen, even though it's a screenshot of my screen at its native resolution.