I've had time to think of some other ones:
The lead character in Prison Break, but only for the first season. They stopped focusing on him and his talents in season 2, and it's dragging for me.
The Evil racist in PB is also a wonder to behold, but as with the lead they've muddled him up in the second season. He's a pure straight-up evil cartoon, and has lost the slimy, human charm he had in S1.
Miles, the smart-ass asian character in Lost. I always found him entertaining.
Sam Malone
Alex P. Keaton
I thought the white-trash character in "the Walking Dead" was extremely well done, but maybe he's just playing himself.
As mentioned before - Captain Mal. And the compainion, just for looks.