<< dude.. Shaq will win! In a real fight, size does matter... this isn't going to be in a ring right?.. by fight you mean if they see each other and just instantously hate each other's guts >>
Yeah, size would matter if neither of them knew how to fight... but boxing and martial arts is the great equalizer, and in this case, Shaq would be down within 10 secs. A single hit from Mike's fist(since it's not in gloves), will put Shaq on the ground whether he hits him in the chin, kidneys, stomach, or even shoulders.