Well, as has been said before, a lot depends upon the engine, loads, etc. the vehicle has and is being used.
In my Chrysler Lebaron turbo, synthetic always. But turbos themselves run HOT, and coking the turbo's bearing after engine shutoff is a very valid concern.
For typical family vehicles, probably just a placebo effect with synthetics, unless the manufacturer specifically calls for its use.
On the other hand, there are many engines around that are known sludge-a-matics. In them, I'd run a synthetic...
I also run synths in my '02 Blazer, mainly due to living in the South (gets hot down here.....has been at or higher than 100F for the last 3-4 weeks not), using it to tow a boat every weekend and tow lots of other crap (two other trailers...one enclosed, one open) from auctions, constant use of the A/C during most of the year (from March-October), and just simple peace of mind given our use of the vehicle. 210K miles and still doesn't burn a 1/2 quart in 5-6K miles. Engine'll probably outlast the rest of the vehicle.