Originally posted by: sdifox
I believe (no scientific backing, but it looks that way) DNA contains a lot of safeguards for the species. Meaning if your DNA meet certain ruls, it will try to kill you off to preserve the species. Cancer is essentially that mechanism working well. I guess untill we got the whole genome figured out, there is no eternal youth. Biomech is a lot more likely.
What you're referring to is a so-called 'autocide gene', some gene (or combination of genes) that causes an individual to die 'for the good of the species' (ie. to prevent overpopulation).
Such genes would contradict what we know about evolutionary theory (there is no such thing as selection at the species level, only at the individual level).
Originally posted by: Gibsons
Originally posted by: Genx87
Isnt there a gene that turns off around age 27-28 causing cell reproduction to slow and the aging mechanism to kick in?
I would imagine if we can isolate that gene we could prolong life. But I think other things like chloresterol or other toxins would eventually catchup with us, but who knows.
You might be thinking of telomerase.
Wiki
Cancer is a whole 'nother ballgame, so to speak. It's a 'normal' senescent process that results from the trade off of investment in the body vs. investment in the gametes. I know I'm splitting hairs, but it's not something that 'kicks in', it's something that gets 'turned off'. Again, think in terms of evolution: what relative reproductive advantage would an organism have if it carried genes that tried to kill it (relative to an organism that didn't have those genes)? Cancer happens when you stop/decrease investing in repairing damaged DNA.
Basically, longevity is something that evolves; current research indicates the major factor in determining an optimum lifespan for an individual is its risk of mortality due to external factors (ie. predation, disease). This is why lifespans tend to increase as you move up the food chain (fewer predators = lower risk of external mortality), and why certain animals live really long.
Ie. before humans came along with their tools, turtles' carapaces proved very effective at keeping them safe, thus, they live a long time. Also, bats, though they're the size of mice, live ~10x as long because they can fly away from danger - same thing for flighted vs. flightless birds: flighted birds live considerably longer than flightless birds despite very their similar biochemistries.
I'd be happy to cite specific articles if anyone's interested, but it should intuitively make sense. Why invest in your body, delaying reproduction, taking a long time to raise offspring, etc. when odds are, a hawk or snake or cat or whatever is likely going to eat you in a matter of days or weeks? That's why mice don't live long at all, they 'turn off' their 'repair genes' quickly after reaching maturity. That's why humans live a relatively long period of time - aside from disease & each other, there's not much that will kill us - so it makes more sense to continue investing in our own repair for quite some time.