Here in geek world Python will win this one going away. I love it too, but think Airplane is funnier as a whole.
A professor of mine in college (who was a huge Python fan) once pointed out that if you took away the English accents suddenly it's nowhere near as funny. I'd never really thought about it that way (it IS considered English humor afterall so the accent goes hand-in-hand with the style) but it does appear to be true somewhat. I can't picture comic actors like the groups from SNL or MadTV or wherever doing the same sequences and finding myself laughing near as hard if I were viewing it for the first time.