RDR2 on the weekends - it's a good weekend title to get absorbed up into, but a little on the slow/tedious side (even compared to LA Noire). Not sure whether I'll keep going with that or switch back to something more familiar this next weekend.
GTA V during the week. Recently got a new, considerably beefier (laptop) rig and the jump in graphics/sound is amazing. Currently getting low on internal HD space though, so if I want to install another easy time-killer (like Far Cry 5), I'll need to score an external SSD.