Still one of the most seductively atmospheric games I've ever played. People still talk about it for good reason. It's worth checking out for anyone who is into computer gaming.
I just finished my first Chinatown missions and discovered the hideout of the Nosferatu, and I wanted to chime in and say how much I agree with this comment. The scene design, ambient sounds, dialog, all of it creates this really eerie, desolate feel to the city. You know a game is well-designed when it so easily overcomes the fact that the gameplay and graphics date from seven years ago. The Nosferatu warrens, in particular, struck me as one of the coolest environments ever. Really got a kick out of that place.
Someone else mentioned that the missions focus more on combat toward the end. I'm not sure how far along I am, but I've noticed there are often simple tactical solutions to seemingly tough boss battles. I won't give anything away here, but there is a simple way to kill the commandos in the Van Helsing experiment at Fu Syndicate, there's a simple way to take out Bishop Vick, and a comically simple and effective way to take out Andre in the first encounter, etc. So far it seems like they usually give you the choice of blasting away or thinking your way out of a situation, and since you can save anywhere you can try different things.
So far this is one of the best Steam bargains ever, for me. Ranks up there with getting Railworks 2 for less than five bucks.