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Vaccines and STDs

Texashiker

Texashiker

Lifer
It seems to me that we have a vaccine for just about everything these days - from the flu to the Rotavirus.

So why dont we have more vaccines for Sexually Transmitted Diseases (STDs)?

Anyone keep up with the HPV vaccine and the uproar it caused? Could you just imagine what would happen if we had a Syphilis, Gonorrhea, Herpes and HPV 4-in-1 vaccine like what kids get with the DTaP?

If we have a vaccine for chicken pox, why dont we have a vaccine for Herpes?
 
Vaccines are only work for viruses. Some viruses work differently, making vaccines is ineffective. Don't wave your wand at the wrong magic show.
 
Texashiker said:
Could you just imagine what would happen if we had a Syphilis, Gonorrhea, Herpes and HPV 4-in-1 vaccine like what kids get with the DTaP?
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Well, the two bolded are bacterial, so that won't work. There is a HPV vaccine. There are also Shingles and Chickenpox vaccines, both zoster forms of herpes. Give it time.
 
SphinxnihpS said:
Vaccines are only work for viruses.
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Pertussis (whooping cough) is a bacteria
Diphtheria which is caused by Corynebacterium diphtheriae is a pathogenic bacterium
Tetanus is bacteria

All three of them are covered by the DTaP vaccine.

There is also a vaccine for tuberculosis (TB), but its rarely given in the USA - TB is a bacteria.
 
HIV vaccines have two problems. One is that HIV attacks your immune system, often disabling it before there is any chance for an immune response. The other is that HIV seems to mutate around attempts at vaccination rather quickly. Antiretroviral drugs taken as post-exposure prophylaxis seem to have slightly more success.

With herpes, there has been more success, and there are vaccines in clinical trials.

Syphilis, chlamydia and gonorrhea are bacterial infections, and thus much harder to develop vaccines for. Until recently, these were fairly easily treated with antibiotics, but they become increasingly resistant, especially to beta-lactams.
 
crashtestdummy said:
HIV vaccines have two problems. One is that HIV attacks your immune system, often disabling it before there is any chance for an immune response. The other is that HIV seems to mutate around attempts at vaccination rather quickly. Antiretroviral drugs taken as post-exposure prophylaxis seem to have slightly more success.

With herpes, there has been more success, and there are vaccines in clinical trials.

Syphilis, chlamydia and gonorrhea are bacterial infections, and thus much harder to develop vaccines for. Until recently, these were fairly easily treated with antibiotics, but they become increasingly resistant, especially to beta-lactams.
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there has not been one vaccine for a retrovirus. hiv is a retrovirus.
 
SandEagle said:
no profit in cures, only treatments.

its 2011. how can we not have a cure for cancer yet?
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Saying that you cured cancer is like saying you've stopped every singleway that a cell can go wrong ever whichis impossible. We may find ways to stop some ways cells become cancerous but curing cancer as a whole is impossible
 
Texashiker said:
It seems to me that if we can have a vaccine for whooping cough, we can have a vaccine for syphilis.

Both have been a plague on mankind of hundreds of years.
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It's not a matter of the impetus and desire, but rather the difficulty of the problem. I'm not enough of an expert on these diseases to tell you exactly what is difficult about generating a vaccine for this particular disease. However, in generating a vaccine, there needs to be some part of the bacteria that your immune system is able to recognize as trigger to a response. This trigger needs to be universally present and not easily mutated around. This is not always available, especially in bacteria, where your immune system has to be able to distinguish between symbiotic an harmful bacteria.

summit said:
there has not been one vaccine for a retrovirus. hiv is a retrovirus.
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There have been many attempts at a vaccine for HIV, most focusing on the envelope proteins. One of the several reasons that these vaccines don't work is that HIV seems to mutate around attempts at vaccinations, and simply develops into a strain that does not respond to developed antibodies.
 
mcmilljb said:
You do realize there are multiple types of cancer right? You can't just cure them all the same way.
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And different stages. People always say dumb things like this and don't even realize the difficulty. It it was all about money, someone would develop a cure and be rich, beyond your imagination. Or a cure would have been developed in the nonprofit/academic space.
 
One rule of thumb to consider for any disease, is that when the normal immune response isn't sufficient to effect a cure, development of a vaccine is likely to be difficult. When the normal immune response in a survivor results in immunity, then vaccine development is typically more successful.

A vaccine for syph might be possible, but don't hold your breath.

Gonorrhea is incredibly tricky, it does some incredibly weird, tricky things. Very counterintuitive wtf type stuff.

Herpes/HSV is within reach. Probably no cure for the infected, but I can't think of technical reasons why a vaccine can't be developed. Social and economic factors are a different story.

As someone mentioned above, there have been at least a few dozen attempts at an HIV vaccine, but only one has shown any sort of success, and that was moderate at best. Otoh, there are people who seem to have immunity, and I'm not just talking about the CCR5 mutants, there does seem to be an effective immune response in some people. Lots of money pouring into this, so there's a genuine chance we'll see a vaccine in the next 10 years imo. But I'm not going to bet on it.
 
SandEagle said:
no profit in cures, only treatments.

its 2011. how can we not have a cure for cancer yet?
Click to expand...

They are afraid of what will happen when they thaw out the Duke. Have you ever taken a cold shower? Multiply that by about a thousand times, thats how pissed off the Duke's gonna be...
 
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