OHH bad idea ya there will be slower loading times! Why would you even think of doing that? Do you not have sata? Even IDE would be a better idea than external at usb 2.0 speeds. Just get yourself a nice cheap sata hardrive and put it in your case. If you don't have the room in your case then I am sure you could change one of the other hardrives to a new bigger one. The prices on hardrives have realy come down.