I clicked the link, but MS' Help & Support Center had nothing to offer. What I'm finding is that this is specific to Application Partitions, which is new to 2K3 Server...?Error: The Template Persistant Cache initialization failed for Application Pool 'DefaultAppPool' because of the following error: Could not create a Disk Cache Sub-directory for the Application Pool. The data may have additional error codes..
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The only recent change I've made is the implementation of Software Update Services, but I've only configured the Client side on a handful of workstations.
If there's a better place for me to post this, I can. Figured it was OS specific enough.
Any advice anyone can offer is greatly appreciated.