DDF anti-wrinkle stuff works. I'm trying out cityface, but it takes a month for the effects to show up so I don't know how effective it is. Just go to a place like Sephora, they're expensive, but you can return it if you're not satisfied, no time limit, you just need to keep the receipt. Regardless, it takes at least 2-4 weeks to show any improvement and you have to keep using it on a daily basis to prevent wrinkles. The above will also slightly reduce existing wrinkles. Expect to pay $60-$80 for the above. Haven't heard of the TNS stuff, but for some reason I'm iffy on things recommended on Oprah. The report about the "real life" book that turned out to be a total fraud doesn't help Oprah's credibility in recommending products either.