Originally posted by: CycloWizard
I may not be on the right track here (it's been a dearly long time since I took genetics - 9 years :-x), but if you're replacing the nucleus to create the clone, why is it difficult to replace it with a nucleus containing the desired DNA?
If you replaced it with a modified nucleus from another egg, that wouldn't be cloning. That's one type of GM and a different and simpler procedure than cloning. Why go to all the extra work of cloning if all you want is genetic modification?
Cloning adds all the extra work of dealing with somatic cells and then convincing a somatic cell nucleus to reproduce once it's in the egg, with all the issues of telomere lengths and such, and there's no reason to do all that extra work if all you want to do is modify the DNA already in the egg.
