My laptop has a 128G M4 for Linux and a Win7 VM, I'm only using half of it tho. I got bit by the OCZ Vertex 2 previously so I am backing up the OS every week and backing up my home dir every 4 hours via snapshots and rsync.
My HTPC has had a Kingston v100+ 64GB for a few months now. I just finished installing Win7 on a 128GB M4 in my main rig last night. Neither system has HDDs inside the case. My main has a 500GB external that I dump my still & video SD cards to and with the move to SSD I added my infrequently used VMs there (Taxes VM, testing VM, ...).
For both HTPC and main I have an iSCSI LUN off my media server with all my games installed. Also have all my media available via CIFS. To top all that off I have a domain set up with roaming profiles and a 10GB slice off an SSD for the profiles and home dirs. The remainder of the SSD is the OS drive for linux (xen HV, 2 linux domUs, 1 XP domU).
So yeah, depending on your use case SSDs can be handy for all sorts of stuff

When they're super cheap I might bother storing games on them, but until then I'm happy with my arrangement.