No, u don't need a special mobo. The main thing needed from the mobo is if u plan on booting from a SCSI HD (Most do), u will need to check the BIOS that it has SCSI as anj option in the boot sequecs. Yeah, you will need an adapter, but not sure what SCSI Card that is so, u may be better off getting a new Tekram, or Adaptec card. Other than the adapter, you just need Cables, Terminators (Both come with Tekram Retail Boxes), and the devices (i.e. Hard Drive's, CD-RW's, CD's, etc).