Well there are 3 main types of SCSI. SCSI-1, SCSI-2, SCSI-3. There are also sub-categories within those main 3, likw Wide, UltraWide, Narrow, Ultra2Wide and so on..
The 50-pin is usually associated with SCSI-1 devices. SCSI-1 devices are those that toppped out at 10MB/SEC max rate. SCSI-2 improved on that, and if I remember correctly used 50-pin aswell, and gave you 20MB/Sec rates..SCSI-3 is usually 68-pin and rates here go from 40 MB/SEC to 160 MB/Sec..
Drives thare are SCSI-3(regular) are backwardly compatible, so you could most definetly pick up a 68-to-50 pin converter and plug it in. The drive will simply reduce it's capabilities depending on the chain it is attached to.
But, this doesn't work with EVERY drive. LVD(Low Voltage Differential) U2W SCSI-3 drives expect a special LVD cable and may not like being plugged into chains that weren't designed for them..Regards