I think recently adaptec had some quality issues, a budy of mine had two dead cards in a row... which is really unusual in any major manufacterer. Anyhow, all scsi is back wards compatible, but will only run at the controller's speed and specs. So any modern drive's advantages will be lost on an older card. So really, you can just buy adapters for all of your drives to make them fit whatever pin array you need. I personally like the tekgram series... I have the 390f and love it because it has BOTH 68pin and 50 pin channels on the same card.