I put an AGP 3850 in to three systems, I talk about it over here
EDIT: Granted all three systems had 4x/8x motherboards but the card should work at 4x in your 2x/4x motherboard. The question is can your power supply provide the extra power the 3850 needs (the card should come with a 2x molex to 6 pin adapter that the card needs if your power supply doesn't have the 6 pin connector).
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