Insidious
Diamond Member
OMG it was such an easy choice.
I have always been drawn to the medical types of projects. Not that these are the only ones that can serve humanity, but I can sense on an inate level, the complexity of the mechanisms that give us life. It only makes sense that the computing power of DC (or something like it) is necessary to begin to build models that are meaningful in terms of todays science. As an engineer I live by a simple rule.... "your answer isn't going to be any better than your model" ie: get rid of those pesky "fudge factors" and it'll work!
With that in mind, I'm sure you can imagine how captivating it is to read things like this in the Rosetta forum, posted by David Baker (project developer):
And beyond all the cool science stuff... this project runs (on the BOINC platform) flawlessly for me. I got it all set up in minutes (literally). I never need to turn it off.. I game, I bring my work home (ORCAD), and of course I pester all of you regularly. Not so much as a sniffle from my system.
The work units are reasonable in size and don't consume the massive amounts of RAM that make us break out the $$ just to support another upgrade... I can decide all the things I want to decide..... cpu usage, sharing% with other projects.... How big a cache I want to keep around....
OK... I'm (edit: almost) done 😀
-Sid
PS: I forgot to meniton... this isn't some hype in a cover page on the front of the site... this is the guy having a conversation with US! The atmosphere in the Rosetta forum is unbelievable.... considerate.... LOTS of involvement from the project developer(s) and a sincere interest in what the participants have to suggest.
An amazing project... I am so excited to be getting in it at the beginning!
I have always been drawn to the medical types of projects. Not that these are the only ones that can serve humanity, but I can sense on an inate level, the complexity of the mechanisms that give us life. It only makes sense that the computing power of DC (or something like it) is necessary to begin to build models that are meaningful in terms of todays science. As an engineer I live by a simple rule.... "your answer isn't going to be any better than your model" ie: get rid of those pesky "fudge factors" and it'll work!
With that in mind, I'm sure you can imagine how captivating it is to read things like this in the Rosetta forum, posted by David Baker (project developer):
... Yes--a difference between this project and other distributed computing projects is that you are actively participating in methods development efforts rather than large scale production level runs. Why are we doing methods development? It is because computational modeling of biological systems is still in its infancy, and if we can make the methods better, we will be able to produce much more accurate and useful models. While Rosetta is probably the best biological structure modeling program in existence today, we feel that it is important to work to make it still better. While you so far have seen the methods development aspect primarily, the program is being used for concrete applications already, for example we just helped build a model of an infectious component of anthrax toxin.
As I said below, we are actively engaged in trying to design a vaccine for HIV. In the near future we will start distributing vaccine design calculations along with the structure prediction methods development calculations, so you will be doing a mix of basic research with long term payoff, and vaccine design with potentially huge short term payoff.
And beyond all the cool science stuff... this project runs (on the BOINC platform) flawlessly for me. I got it all set up in minutes (literally). I never need to turn it off.. I game, I bring my work home (ORCAD), and of course I pester all of you regularly. Not so much as a sniffle from my system.
The work units are reasonable in size and don't consume the massive amounts of RAM that make us break out the $$ just to support another upgrade... I can decide all the things I want to decide..... cpu usage, sharing% with other projects.... How big a cache I want to keep around....
OK... I'm (edit: almost) done 😀
-Sid
PS: I forgot to meniton... this isn't some hype in a cover page on the front of the site... this is the guy having a conversation with US! The atmosphere in the Rosetta forum is unbelievable.... considerate.... LOTS of involvement from the project developer(s) and a sincere interest in what the participants have to suggest.
An amazing project... I am so excited to be getting in it at the beginning!