• We’re currently investigating an issue related to the forum theme and styling that is impacting page layout and visual formatting. The problem has been identified, and we are actively working on a resolution. There is no impact to user data or functionality, this is strictly a front-end display issue. We’ll post an update once the fix has been deployed. Thanks for your patience while we get this sorted.

Rosetta@Home

M

mrwizer

Senior member
It seems Rosetta@Home is still in open Beta phase. I did not see a team yet, so I created one. Join here.

Anyone know what the exact difference is between this project, Folding@Home, and Predictor@Home? Seems to be a lot of protein projects lately.
 
From the message board:

Both projects are similar in that both are trying to improve methods for protein structure prediction. Rosetta@home includes protein design and prediction of complexes. Rosetta@home uses a software package called Rosetta, which has been proven to be one of the best methods out there for protein structure prediction in repeated CASP experiments (See our About page). Rosetta is also being used for the Human Proteome Folding Project, which is trying to predict folds for many proteins in the human genome. While they, in collaboration with us, are applying Rosetta to the human genome and other genomes like malaria (P falciparum), we are trying to conduct research to make it better. David Baker's work has been published in today's issue of Science. It is exciting work. Thank you for your interest in helping our and similar projects, like Predictor@home!!!
 
And one more...

How does Rosetta@home differ from Folding@Home and the World Community grid's human proteome project?

Folding@home studies the process of folding using molecular dynamics. Distributed computing is allowing them to do simulations at time scales (milliseconds) that are not possible without thousands of computers. We, on the other hand, are doing protein fold predictions and design, including protein complexes. The WCG project is applying our Rosetta software to the human genome and other genomes, in collaboration with our group. We are trying to improve the software (focusing on research, development, and testing).

For example, what we learn through our project may help the WCG in their next phase for high-resolution structure prediction.

 
Thanks for the info, I'm joined up!

As Rosetta uses a LOT of RAM, 150 - 225 MB, I only have a few machines that have enough to spare for running it. I loaded it up here at work on a few machines and 2 minutes later I get "Hey, how come my machine's running so slow!" It's a Win2K box with 384 and couldn't spare the 145mb of RAM Rosetta sucked up. So those machines will just have to suffice with SETI, Protein and Einstein.

What's interseting about the RAM usage is that the Rosetta project through UD only uses about 50mb. Unfortunately I'm not gonna run them till they get their act together. Having to re-register all my machines 2 to 3 times in a one month period was just too much hastle and loss of computing time for me.
 
You must log in or register to reply here.

TRENDING THREADS

Back
Top